Biktarvy (Bictegravir/Emtricitabine/Tenofoviralafenamide)

What is Biktarvy?

Biktarvy is a brand prescribed medication used to treat HIV-1 infection. It is a combination antiretroviral medication intended to boost immune system performance and lower blood viral load. It is a one fixed dose combination medication with three active components:

• Bictegravir is an integrase strand transfer inhibitor (INSTI) that inhibits HIV virus replication by blocking the integration of viral DNA into the DNA of the host cell.
• Emtricitabine plays a role in reverse transcriptase by the nucleoside reverse transcriptase inhibitor (NRTI).
• Tenofovir Alafenamide Another NRTI that functions by blocking reverse transcriptase and obstructing viral replication is comparable to emtricitabine.

It is generally prescribed for the treatment of HIV-1 infection in adults and children weighing 25 kg or. It is usually not recommended for HIV-2 and patients with severe liver issues.

How to use Biktarvy?

• Biktarvy is a wholesome one dose of combination medication which contains three different ingredients working on three different mechanisms.
• The 50 mg dose of bictegravir prevents the incorporation of viral DNA into host DNA. Emtricitabine, a 200 mg dose that prevents HIV replication by inhibiting reverse transcriptase. Tenofovir alafenamide (25 mg), which inhibits viral replication in a manner akin to that of emtricitabine.
• The recommended dosage of Biktarvy is one oral tablet once a day.
• Each tablet has 200 mg of Emtricitabine, 25 mg of Tenofovir Alafenamide, and 50 mg of Bictegravir.
• It can be taken with or without food.
• Take the medication down completely with some water.
• Avoid crushing or chewing the pill.

What is Biktarvy used for?

Biktarvy is a brand prescribed medication used to treat HIV-1 infection. Alongwith this some other uses of it are:

• Reducing the blood level of HIV-1 (viral load) to undetectable levels is the main objective of the Biktarvy therapy. This lowers the risk of spreading the virus to others and aids in the efficient management of the condition.
• Biktarvy helps to strengthen the immune system, which is essential for warding against illnesses and preserving general health, by inhibiting the virus.
• It works well and helps stop or postpone the emergence of opportunistic infections and HIV-related problems, which can happen when the immune system is weakened.
• Biktarvy is not recommended for the treatment of HIV-2 infection and is only used to treat HIV-1 infection.

Biktarvy Side Effects:

Usually minor, some adverse effects which could become better as your body gets used to the medication include a comprehensive list of:

• Diarrhea
• Nausea
• Abdominal pain
• Headache
• Tiredness

Some rare side effects can also occur. Be aware if any of the below listed symptoms goes persistent or worse. In such case seek immediate medical intervention:

• Liver Issues like jaundice, or yellowing of the skin or eyes, dark urine, chronic nausea, stomach discomfort, or extreme fatigue.
• Kidney damage symptoms like Reduced kidney function might show up as unusual fatigue, alterations in urine, or edema in the legs or feet.
• Tenofovir Alafenamide usage for an extended period may result in reduced bone mineral density, which may raise the risk of fractures.
• Rashes, swelling, or itching are examples of uncommon allergic responses.
• Some people may go through phases of despair or anxiety, or they may suffer mood swings.

What are the Safety/Warnings for Biktarvy?

Here are some drug interactions to be aware of:

• Individuals with pre-existing liver problems, such as chronic hepatitis B or C, should exercise caution when using Bictarvy since it may impact liver function. Testing liver function regularly is advised to keep an eye on liver health.
• Kidney function may be impacted by one of Biktarvy's ingredients, Tenofovir Alafenamide. Patients who already have kidney disease or who are at risk of developing renal impairment should use caution. To keep an eye on any possible effects on the kidneys, routine testing for renal function is required.
• Tenofovir Alafenamide usage for an extended period may result in reduced bone mineral density, raising the risk of fractures.
• You should talk to your healthcare practitioner about the advantages and disadvantages of using Biktarvy while pregnant or nursing.
• One should strictly follow the prescribed dosage regimen to avoid viral resistance which can reduce the effectiveness of the medication.

Biktarvy Drug Interactions:

Some of the commonly known drug interactions with Biktarvy include:

• The efficacy of Bictegravir can be reduced by anticonvulsants such as phenytoin, carbamazepine, and phenobarbital by lowering its levels.
• Since rifamycins can dramatically lower Bictegravir levels, it is typically not advised to use them with Bictarvy.
• Steer clear of St. John's Wort if you are taking Biktarvy. Talk to your doctor about any herbal supplements or complementary therapy.
• When used with Tenofovir Alafenamide, some diuretics and nonsteroidal anti-inflammatory medications (NSAIDs) may increase the risk of kidney damage.
• High doses of some drugs, such as methotrexate and acetaminophen, can raise the risk of liver damage.
• The majority of drugs, which are prescribed for common ailments like high blood pressure, diabetes, and cholesterol, do not influence how well Biktarvy works. To prevent unanticipated interactions, you must inform your healthcare professional of all of the drugs you are taking.
• Biktarvy might not be advised for individuals with moderate to severe hepatic or renal impairment. Speak with your healthcare professional.

Biktarvy Dosage:

Here are some general guidelines for storing Pristiq tablets:

• The commonly recommended dose for Bikatravy is one Tablet orally once a day.
• You can take Bictarvy with or without meals. There are no particular dietary requirements or modifications needed.
• When taking the pill, drink a glass of water.
• Never split, chew, or crush the pill.
• Take your Biktarvy dosage as soon as you remember if you miss one. Do not take two doses at once to make up for a missed dosage; if your next dose is soon due, omit the missing one.
• Make an effort to take Biktarvy at the same time every day to sustain a successful treatment regimen and efficient viral suppression.

Biktarvy Storage:

• Store Baktarvy at room temperature, around 68°F to 77°F (20°C to 25°C),. Keep the drug away from extremely hot or cold conditions.
• Store Biktarvy away from moisture. It should not be kept in a bathroom or any other area where it might come into contact with moisture.
• To keep Biktarvy safe from light and moisture, store it in its original container and make sure the lid is well closed.
• Keep Biktarvy out of the reach of kids and animals to avoid abuse or unintentional intake.
• Follow any municipal laws or disposal recommendations when discarding any unused or expired Biktarvy pills.

What is the Biktarvy Cost:

Biktarvy is one of the effective medications used for the treatment of HIV-1. Biktarvy cost can vary based on many factors like its strength, dosage, quantity manufacturer country, local medication dispensing pharmacy and your covered insurance plan.

Based on current projections, on average a 30-day supply of (one tablet per day) Biktarvy price is somewhere between $3,000 and $4,000.

Is it safe to buy Biktarvy online from an Online Pharmacy?

One can safely buy Bikatarvy online through a legitimate, licensed online pharmacy that requires a valid prescription. Buying Bilatravy online not only offers the most competitive affordable Bikatarvy price, it also aids in saving your time, money, and energy. One can easily check and compare the different prices offered at retailers or online pharmacies and choose the most affordable deal for them.

To ease your options Medsengage is one of the most reliable and trusted online pharmacies which offers a wide range of both generic and brand-prescribed medication at a cheap price.

It is a highly committed service provider with convenient, reliable, and secure access to medications and healthcare products. They work to enhance your health and well-being through a seamless and user-friendly online experience.

FAQs:

How long does Biktarvy stay in your system?

After the last dosage, Bictarvy usually remains in your system for one to two days. This is because of its half-lives: Bictegravir, one of its constituents, has a half-life of around 15-20 hours, whereas the half-lives of emtricitabine and Tenofovir Alafenamide are approximately 10 hours and 0.5-1 hour, respectively.

Can i drink alcohol with Biktarvy?

Yes, using Biktarvy and moderate alcohol intake is typically considered safe. On the other hand, drinking too much alcohol might harm your general health and perhaps reduce the efficacy of your treatment. Always seek individual guidance from your healthcare practitioner.

What happens if i miss a week of Biktarvy?

Biktarvy's efficacy may be reduced and the risk of HIV resistance may rise if a week is missed. For advice on how to restart taking your medicine and to discuss any actions that may be required to handle missing doses, get in touch with your healthcare professional.

Does Biktarvy cause Erectile Dysfunction?

It is rare for erectile dysfunction to be listed as a Biktarvy side effect. Individual reactions to drugs can differ, though. While using Biktarvy, if you encounter erectile dysfunction or any other concerning symptoms, speak with your doctor about possible causes and course of action.

Can Biktarvy be used for prep?

Biktarvy is not used in pre-exposure prophylaxis, or PrEP, for that reason. Different drugs, such as Truvada or Descovy, are part of PrEP that is especially designed to prevent HIV infection.

References:

• https://www.webmd.com/drugs/2/drug-174749/biktarvy-oral/details
• https://www.biktarvy.com/