Nexavar (Sorafenib)

Mechanism of action of Nexavar:

Sorafenib works by inhibiting the enzymes, tyrosine protein kinases, including VEGFR, PDGFR as well as Raf family kinases. As a result, the medication induces autophagy, which in turn suppresses the growth and development of tumour.

How to take Nexavar?

Nexavar is always taken exactly as per the doctor’s instructions. The recommended dose of this medication is 400 mg (or two tablets) by mouth two times on a daily basis. The dose reduction may be required for managing alleged adverse drug reactions. The reduction of dose can be done to 400 mg once daily or to 400 mg every other day. The medicine must be taken on an empty stomach i.e. without food.

In case of missed dose:

In case you skip taking a dose, you must take it as soon as you become aware of. If it is nearly the time of your next dose, you may leave out the missed dose and start again with your dosing plan. Avoid taking additional dose to make up for a missed dose. If you are frequently missing doses, then set an alarm or ask your family member to jog your memory. Also contact your practitioner for discussing modifications in your dosing timetable or a new timetable to make up for missed doses, if you have missed too many doses lately.

Side effects:

The common side effects which can occur after taking this medication include:

• Anorexia
• Vomiting
• Nausea
• Constipation
• Indigestion problems
• Dyspepsia
• Altered voice
• Difficulty in swallowing
• Distorted taste and tiredness, etc.

If these disagreeable effects become bothersome to continue with your daily life, then your physician can help.

Drug-Drug Interactions:

If you take other medications at the same time along with this medicine, the effects of Sorafenib may get altered. This may augment your risk for side-effects or result in non-efficacy of your medicine. Thus it is important to inform your doctor about all the medications or supplements that you are using, in order that he or she can help you manage or prevent harmful drug interactions.

Nexavar tablet is thought to interact with the following drugs:

• Carbamazepine
• Phenobarbital
• Phenytoin
• Ketoconazole
• Neomycin
• Rifabutin
• Rifampin
• Dexamethasone

Precautionary measures:

• Avoid the use of this medication if you are suffering from or having a history of the following medical conditions: heart issues, chest pain, cardiovascular problems like high blood pressure, bleeding problems.
• Do not take Nexavar tablet if you are having kidney or liver disorders.
• Monitoring of blood calcium levels, electrolyte balance as well as thyroid hormones is very crucial while taking this drug.
• If you are pregnant, planning to get pregnant or are breastfeeding, in all the three cases this drug is not good for you.

Is it safe to buy Nexavar from a Online Pharmacy?

If you are looking to buy Nexavar or any prescription drugs from an Online Pharmacy USA then you can order from a safe and accredited International pharmacy like MedsEngage, which contracts with Canadian Pharmacy and pharmacy in India. you requires a valid prescription for your prescription drugs.