Ofev (Nintedanib)
Nintedanib (Ofev) is a prescription medication used to treat idiopathic pulmonary fibrosis (IPF) and nonsmall cell lung cancer (NSCLC). Nintedanib belongs to a class of drugs called tyrosine kinase inhibitors. A class of drugs is a group of medications that work similarly. They have a similar chemical structure and are often used to treat similar conditions. Select your dosage below to view Ofev cost and place your order. Save up to 80% on Ofev price when you buy Ofev online from our online pharmacy..
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Buy Ofev (Nintedanib) Online: Medication Information
What is Ofev?
Nintedanib, also known as Ofev, is a medication used to treat idiopathic pulmonary fibrosis (IPF). IPF is a chronic, progressive lung disease characterized by the buildup of scar tissue in the lungs.
What is Ofev used for?
Nintedanib is a small molecule that inhibits multiple tyrosine kinases. It was approved in the United States in 2014 for the treatment of idiopathic pulmonary fibrosis. Nintedanib is also being studied for the treatment of other diseases, including liver fibrosis, ovarian cancer, and non-small cell lung cancer.
How does Ofev work?
Nintedanib works by inhibiting the activity of certain enzymes that are involved in the growth and repair of connective tissue. This helps to slow the progression of IPF and improve symptoms.
What are the side effects of Ofev?
The most common side effects include:
Diarrhea
Nausea
Vomiting
Abdominal Pain
Fatigue
Less common side effects include:
Headache
Muscle pain
Difficulty sleeping
Nintedanib may also cause more serious side effects, such as liver damage, kidney damage, and bleeding. If you experience any of these side effects, you should contact your doctor immediately.
Interaction with Ofev:
Some medications that may interact with nintedanib include: amiodarone, aprepitant, bosutinib, carbamazepine, clarithromycin, cyclosporine, dasatinib, digoxin, erythromycin, fluconazole, itraconazole, ketoconazole, lapatinib, levothyroxine, modafinil nefazodone, telithromycin, warfarin etc.
Ofev Cost:
Depending on your pharmacy, the average Ofev cost in the US market is roughly $14,197.57 for a supply of 60 capsules based on the country's product.
Since there isn't yet a generic version available in the market, it is expensive and can be out of reach for some people. Most Medicare and insurance programs cover Ofev Medications because of the high Ofev cost.
Why is Ofev so expensive in local pharmacies?
Drug prices are monitored globally, including in the United States and Canada. Pharmaceutical companies are free to determine their rates, which explains why there are different prices for Nintedanib because the generic version is still not available everywhere. The Food and Drug Administration, drug distributors, and pharmacies with Nintedanib manufacturing patents decide the costs for certain pharmaceuticals among the many pharmaceutical businesses.
Before a prescription reaches the customer, it has to follow a long path through the supply chain. For 60 capsules, the Brand Ofev cost at a local US drugstore was typically around $14,197.57. You can reduce this expense when you buy Ofev online from MedsEngage.
References:
- https://www.mayoclinic.org/drugs-supplements/nintedanib-oral-route/description/drg-20071401
- https://medlineplus.gov/druginfo/meds/a614009.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/205832s000lbl.pdf
FAQs:
How long for Ofev to start working?
Just like any other medicine, Ofev starts working in the patient’s body soon after the treatment course is started. But, its working may not be noticeable so a doctor may do some tests to check for its working. As per clinical trials of patients prescribed Ofev, it was noticed that the medicine started slowing the progression of conditions like idiopathic pulmonary fibrosis (IPF) and interstitial lung disease in about 6-12 weeks.
How long does Ofev stay in your system?
It depends on how the patient's body responds to Ofev and processes it to eliminate the drug from the system. A half-life of a drug is the time taken for the drug’s active substance to be reduced to half after the treatment course ends. Ofev contains Nintedanib as the active ingredient which is known to have a terminal elimination half-life of around 10 to 15 hours.
What happens if you stop taking Ofev?
Sudden discontinuation of any medication like Ofev without a doctor's recommendation and supervision can lead to many unwanted effects on the body. Currently, there isn’t enough research evidence detailing the response of IPF to stopping Ofev intake. However, it has been noticed that stopping intake of nintedanib-containing drugs may severely affect the lungs within 3 weeks.
Does Ofev cause hair loss?
Hair loss may be one of the side effects of taking Ofev. However clinical studies on people taking Ofev reveal hair loss as a rare side effect. Hair loss may occur due to low thyroid levels, rarely caused by intake of Ofev.
Does Ofev cause fatigue?
Fatigue or extreme tiredness is not one of the most common side effects reported by patients taking Ofev. Still, some patients may experience low energy or tiredness and may not be able to perform their usual activities while taking Ofev.
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