Rapamune (Sirolimus)

What is Rapamune (Sirolimus)?

A prescription drug called Rapamune is used to treat the symptoms of Lymphangioleiomyomatosis and Prophylaxis of Renal Transplant Rejection. Rapamune may be used alone or in combination with other drugs. Rapamune is a member of the immunosuppressant drug category.

What is Rapamune (Sirolimus) used for?

When a kidney transplant recipient is 13 years of age or older, the anti-rejection medication Rapamune is used to avoid organ rejection. Rejection occurs when the new organ is attacked by the immune system of your body because it perceives it as a "foreign" threat. Rapamune is used with corticosteroids and other medications containing cyclosporine to avoid organ rejection by the body.

How does Rapamune (Sirolimus) work?

In order for your body to accept the new organ as if it were your own, it works by weakening your immune system. It is a medication that reduces the body's built-in defenses. Nephrotic Syndrome is believed to be caused by an immunological response. Additionally, it is used to stop the rejection of transplanted organs like the liver, heart, and kidney.

Direction for Use:

How to take Rapamune (Sirolimus)?

As prescribed by your doctor, take this medication by mouth once daily. Completely swallow this medication. The tablets must not be chewed, split, or crushed. You can take this medication with meals if you are experiencing nausea or an upset stomach. However, it's crucial to take this medication consistently with each dose, whether with or without meals.

What is the different dosage available for Rapamune (Sirolimus)?

The dosage is offered as an oral tablet of 0.5mg, 1mg, and 2mg depending on the line of treatment chosen.

What is the recommended dosage for Rapamune (Sirolimus)?

The recommended initial dose of Rapamune is 2 mg daily.

What if you forget to give a dose of Rapamune?

Get the missed dose as soon as you recall. If the next dose is approaching, skip the missed dose and resume your usual dosing schedule.

Precautions for Entresto (Sacubitril):

What should you know about Rapamune (Sirolimus) before you start taking it?

• If you are allergic to sirolimus or if you've ever had a liver or lung transplant, you shouldn't use Rapamune.

• Your immune system may be affected by Rapamune, which may result in the overproduction of some types of white blood cells. It can cause cancer, a fatal or seriously disabled brain illness, or a viral infection that prevents kidney transplant success.

• Tell your doctor if you have a history of liver illness, cytomegalovirus (CMV), high cholesterol or triglycerides, liver disease, or a family history of skin cancer (melanoma).

Side-Effects of Rapamune (Sirolimus):

What are the side effects of Rapamune (Sirolimus)?

Rapamune's common side effects include:

• Upper respiratory tract infection

• Urinary tract infection

• Diarrhea

• Joint pain

• Tremors

• Acne

• Sleep Issues

Some serious side effects of Rapamune have the potential to induce:

• A fatal or seriously incapacitating brain infection

• Changes in your mental state

• Poor vision

• Weakness on one side of your body

• Speaking or walking issues

Call your doctor right away. These symptoms could develop gradually before rapidly worsening therefore one should pay close attention to them.

Interaction with Rapamune:

Does this medication interact with other drugs, foods, or alcohol?

Inform your doctor of all the medications you are taking. Rapamune potentially interacts with many other diseases like bromocriptine, cyclosporine, danazol, and tacrolimus; drugs that reduce cholesterol, an antifungal or antibacterial drug, antiviral medication to treat hepatitis C or HIV, blood pressure or cardiac medicine, medication to treat an ulcer or lower stomach acid or medication for seizures.

Storage:

How should this medication be stored?

Rapamune (Sirolimus) should be kept at room temperature (15-30 degrees) and away from light, heat, moisture, and children's access.

Other Important Information:

• The Medication should not be used without a doctor’s prescription.

• If you've ever had a liver or lung transplant, you shouldn't use Rapamune.

• Before receiving any immunizations or vaccinations, let your healthcare provider know that you are taking Sirolimus.

• Your risk of getting skin cancer could go up if you take this medicine. Avoid going out in the sun. Avoid using sunlamps and tanning booths. When outdoors, wear protective gear and sunscreen.

• Call your doctor right away if you experience any of the flu-like symptoms, burning when you urinate, a new skin lesion, any mental changes, reduced vision, weakness on one side of your body, issues speaking or walking, or pain around your transplant.

Is It Safe To Buy Rapamune From an Online Pharmacy?

If you are looking to buy Rapamune or any prescription drugs from an in the USA then you can order from a safe and accredited International pharmacy like MedsEngage, which contracts with Canadian Pharmacy and pharmacy in India. You require a valid prescription for your prescription drugs.

FAQs:

Are Sirolimus and Rapamune the same thing?

A medication that decreases the body's natural immunity is sirolimus, sometimes referred to as rapamycin or by the brand name Rapamune. Nephrotic Syndrome is hypothesized to be caused by an immunological response. It is used to stop the rejection of transplanted organs like the liver, heart, and kidney.

How does Rapamune work in the body?

Rapamune prevents the white blood cells from removing the donated organ, which is how it functions. The drug Rapamune is quite potent. Additionally, it can make the body less able to fight infections.

Do side effects from Rapamune disappear?

Rapamune may cause several adverse effects, most of which do not require medical treatment. During therapy, these side effects could fade away as your body gets used to the medication. Additionally, your healthcare provider might be able to provide you with information on how to avoid or lessen some of these adverse effects.

Can I drive after taking Rapamune?

It's not advisable to drive or operate machinery if you have vertigo, drowsiness, or any of these side effects with this medication.

Can I take Rapamune during pregnancy?

Do not use this medication if you are pregnant or suspect that you might be pregnant since it could harm the unborn child.

References:

• https://pubchem.ncbi.nlm.nih.gov/compound/Sirolimus#section=2D-Structure
• https://www.drugs.com/pro/rapamune.html